Input to the plotTMB function to be used in tests

Table containing estimated tumor mutational burden and metadata (sample, filter, size of the sequenced genomic space) calculated using 4 patients from the VanAllen et al. dataset.

TMB_VanAllen

Format

A data frame with 16 rows and 5 variables

Sample

factor, sample identifier

Filter

factor, type of filter, if any, applied on input mutations

Sequencing_Size

numeric vector, genomic size targeted by the sequencing experiment (WES or Panel), in Mb

Design

Name of the panel experiment

Tot_Number_Mutations

numeric vector, tumor mutational burden in the targeted genomic region

TMB_per_Mb

numeric vector, global tumor mutational burden expressed as number of mutations

Source

Dataset from Van Allen EM et al., Science 2015