Input to the plotTMB function to be used in tests

Table containing estimated tumor mutational burden and metadata (sample, filter, size of the sequenced genomic space) calculated using the Horizon demo dataset

TMB_Horizon

Format

A data frame with 16 rows and 5 variables

Sample

factor, sample identifier

Filter

factor, type of filter, if any, applied on input mutations

Sequencing_Size

numeric vector, genomic size targeted by the sequencing experiment (WES or Panel), in Mb

Tot_Number_Mutations

numeric vector, tumor mutational burden in the targeted genomic region

TMB_per_Mb

numeric vector, global tumor mutational burden expressed as number of mutations

Source

generated in house as an example using a custom Panel and toy examples of VCF files from Horizon cell line dataset